Table 2:
Multivariate Analysis of OS
ND (n = 34) | MD (n = 34) | HD (n=33) | ||||
---|---|---|---|---|---|---|
Variable | HR (95% CI) | p Value | HR (95% CI) | P-Value | HR (95% CI) | p Value |
Age | ||||||
>=65 yrs | 1.02 (1.00 – 1.06) | 0.06 | 1.51 (0.52 – 4.43) | 0.45 | 1.71 (0.78 – 3.73) | 0.17 |
KPS score | ||||||
>=70 | 0.41 (0.16 – 0.99) | 0.05 | 0.34 (0.12 – 0.94) | 0.03 | 0.27 (0.08 – 0.95) | 0.04 |
MGMT | ||||||
Methylated | 0.32 (0.13 – 0.79) | 0.01 | 0.63 (0.52 – 0.99) | 0.04 | 0.75 (0.39 – 1.41) | 0.36 |
Contact w/ Ventricles | 1.21 (1.10 – 1.63) | 0.02 | 1.26 (1.13 – 1.78) | 0.03 | 1.56 (1.34 – 1.85) | 0.03 |
FLAIR SMR | 0.99 (0.98 – 1.00) | 0.53 | 0.99 (0.98 – 0.99) | 0.02 | 0.98 (0.96 – 0.99) | 0.04 |
> 10% | 0.28 (0.09 – 0.93) | 0.03 | 0.35 (0.13 – 0.91) | 0.03 | 0.48 (0.16 – 1.44) | 0.19 |
> 20% | 0.56 (0.35 – 0.89) | 0.01 | 0.27 (0.12 – 0.66) | <0.01 | 0.58 (0.24 – 1.38) | 0.22 |
> 30% | 0.75 (0.51 – 3.49) | 0.55 | 0.26 (0.10 – 0.63) | <0.01 | 0.39 (0.17 – 0.92) | 0.03 |
> 40% | 0.98 (0.35 – 2.91) | 0.97 | 0.27 (0.11 – 0.63) | <0.01 | 0.36 (0.16 – 0.83) | 0.02 |
> 50% | 0.88 (0.29 – 2.28) | 0.78 | 0.36 (0.15 – 0.86) | 0.02 | 0.26 (0.10 – 0.63) | <0.01 |
> 60% | 0.82 (0.37 – 1.81) | 0.62 | 0.68 (0.29 – 1.60) | 0.38 | 0.27 (0.11 – 0.63) | <0.01 |
> 70% | 0.68 (0.29 – 1.60) | 0.38 | 0.77 (0.32 – 1.84) | 0.55 | 0.35 (0.13 – 0.91) | 0.03 |
> 80% | 0.64 (0.24 – 1.70) | 0.37 | 0.68 (0.25 – 1.82) | 0.44 | 0.56 (0.35 – 0.89) | 0.01 |
> 90% | 0.52 (0.18 – 1.51) | 0.23 | 0.82 (0.35 – 2.26) | 0.33 | 0.62 (0.39 – 0.99) | 0.04 |
Boldface type indicates statistical significance.