TABLE 3:

Multivariate analysis of SMR and OS

Variable	HR (95% CI)	p Value
% SMR on T2-weighted FLAIR
Increased Resection	0.99 (0.98 – 0.99)	0.02
> 20%	0.56 (0.35 – 0.89)	0.01
> 30%	0.55 (0.35 – 0.87)	0.01
> 40%	0.52 (0.33 – 0.81)	<0.01
> 50%	0.62 (0.39 – 0.99)	0.04
> 60%	0.74 (0.45 – 1.21)	0.34
Age ≥ 65 yrs	1.61 (1.01 – 2.56)	0.04
KPS ≥ 70	0.48 (0.27 – 0.89)	0.02
Charlson Comorbidity Index	1.07 (1.01 – 1.16)	0.03
MGMT promoter methylation	0.63 (0.52 – 0.99)	0.04
Contact w/ LVs	1.26 (1.13 – 1.78)	0.03
T1/T2-weighted FLAIR ratio	0.97 (0.94 – 1.02)	0.38
Deep-seated tumor	1.21 (0.66 – 2.16)	0.46

Boldface type indicates statistical significance (p < 0.05).