Table 3. Logistic regression analyses for the association between antiplatelet medication and CMBs.
| Variables | Unadjusted | Model 1 | Model 2 | |||||
| OR (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value | |||
| Model 1: adjusted for age and sex. Model 2: adjusted for variables in model 1 plus history of smoke, hypertension, atrial fibrillation, antihypertensive medication use, lipid-lowering medication use, oral hypoglycemic agents or insulin, hemoglobin A1c level, and low-density lipoprotein cholesterol level. CMB: cerebral microbleed; OR: odds ratio. | ||||||||
| Any CMB | 4.52 (2.63–7.77) | < 0.001 | 2.38 (1.33–4.26) | 0.005 | 2.39 (1.24–4.58) | 0.009 | ||
| Lobar CMBs | 5.46 (2.99–9.95) | < 0.001 | 2.90 (1.53–5.49) | 0.001 | 2.83 (1.36–5.86) | 0.005 | ||
| Any lobar CMBs (Lobar CMBs + Mixed CMBs) | 5.06 (2.86–8.93) | < 0.001 | 2.62 (1.43–4.82) | 0.002 | 2.53 (1.27–5.04) | 0.008 | ||
| Deep or infratentorial CMBs | 2.59 (0.83–8.06) | 0.102 | 1.48 (0.46–4.81) | 0.511 | 1.63 (0.44–6.02) | 0.461 | ||
| Any deep CMBs
(Deep or infratentorial CMBs + Mixed CMBs) |
2.98 (1.27–6.98) | 0.012 | 1.55 (0.64–3.78) | 0.332 | 1.63 (0.62–4.32) | 0.324 | ||