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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: DNA Repair (Amst). 2022 Feb 17;112:103301. doi: 10.1016/j.dnarep.2022.103301

Figure 4. Structural diversity of histone H2A variants within the nucleosome core particle.

Figure 4.

The side view of the crystal structures of human nucleosome core particles with either canonical or H2A variants is shown to highlight the location of the L1 loops of the H2A variants. A close-up view of the L1 loop region of the canonical and of each H2A variant is shown. Canonical H2A (PDB ID: 5Y0C) [16], H2A.X (PDB ID:6K1J) [63], mH2A (PDB ID:1U35) [57], H2A.Z.1 (PDB ID: 3WA9) [55] and H2A.Z.2 (PDB ID:3WAA)[55]. Nucleosome core particle figures were made using PyMol software.