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. 2022 Jun 17;13:896006. doi: 10.3389/fphys.2022.896006

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Copyright © 2022 Shen, Miao, Vu, Xu, González-Zacarías, Nederveen and Wood.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Relationship between OEF-TRUST with left shifted hemoglobin. Linear correlations are shown in blue line (r ² = 0.46, p = 0.0027) for ACTL and red line (r ² = 0.35, p = 0.0018) for SCD. The control group is shown as 36.8 ± 5.5 (mean ± std) in green. (B) Relationship between corrected OEF-TRUST with O₂ content.