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. 2022 Jun 17;13:896006. doi: 10.3389/fphys.2022.896006

TABLE 2.

Differences between hemoglobin F, hemoglobin S and OEF by three methods with or without hydroxyurea (HU) for non-transfused SCD patients.

With HU Without HU p-value
Hb 9.5 ± 1.4 12.1 ± 2.7 < 0.001
Hb F (%) 18.4 ± 8.8 1.4 ± 3.3 < 0.001
Hb S (%) 78.2 ± 8.3 18.2 ± 27.9 < 0.001
OEF-TRUST (%) 28.2 ± 6.1 35.3 ± 5.7 < 0.001
OEF-CISSCO (%) 42.9 ± 5.5 36.2 ± 5.2 < 0.001
OEF-QSM (%) 30.1 ± 4.4 28.0 ± 2.7 0.1034

Bold text depicts a p-value < 0.05.