TABLE 1.
Body composition, energy intake and metabolic and inflammatory parameters after 28 weeks.
| HFD + vehicle | HFD + 2′-FL | |
| Average food intake (g/day) | 2.5 ± 0.2 | 2.6 ± 0.3 |
| Body weight (g) | 46.8 ± 4.2 | 47.4 ± 4.7 |
| Fat mass (g) | 19.5 ± 3.1 | 19.9 ± 3.6 |
| Fat mass (%) | 42.5 ± 4.2 | 42.5 ± 4.0 |
| Lean mass (g) | 26.2 ± 2.1 | 26.6 ± 3.6 |
| eWAT (g) | 2.2 ± 0.4 | 2.4 ± 0.6 |
| mWAT (g) | 1.0 ± 0.3 | 0.9 ± 0.3 |
| sWAT (g) | 2.6 ± 0.7 | 2.5 ± 0.6 |
| Plasma leptin (ng/ml) | 48.4 ± 13.5 | 46.4 ± 10.5 |
| Plasma adiponectin (μg/ml) | 9.9 ± 3.5 | 10.0 ± 2.8 |
| Plasma MCP-1/CCL2 (pg/ml) | 15.7 ± 8.7 | 9.6 ± 4.0* |
| Plasma MIF (μg/ml) | 32.0 ± 14.5 | 22.1 ± 14.9 |
| Plasma SAA (μg/ml) | 18.8 ± 4.6 | 19.5 ± 4.1 |
| Plasma Fetuin A (μg/ml) | 46.1 ± 7.7 | 44.4 ± 10.8 |
| Plasma cholesterol (mM) | 31.0 ± 7.8 | 29.9 ± 8.4 |
| Plasma triacylglycerol (mM) | 6.5 ± 2.4 | 5.8 ± 2.6 |
eWAT = epididymal white adipose tissue, mWAT = mesenteric white adipose tissue and sWAT = subcutaneous white adipose tissue. Data are presented as mean ± SD. Asterisks indicate a significant difference relative to HFD + vehicle control (*p < 0.05).