Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Dec 29;24(7):1150–1163. doi: 10.1093/neuonc/noab300

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021. Published by Oxford University Press on behalf of the Society for Neuro-Oncology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

PMC Copyright notice

Fig. 4 — Effect of BMS and LIN treatments on GD2-CAR T-cell phenotypes. (A) IFNα (left panel) and TNFγ (right panel) mRNA levels in 1A7-activated CAR-T cells treated with BMS, LIN, or DMSO as vehicle control. Data are normalized to the nonactivated CAR-T cells (CTR). Results are presented as mean ± SD of 3 independent repeats. (B–D) Box-plots representating activation (B), exhaustion (C), and memory (D) profiles of CAR or NT T-cells in coculture for 96 h with or without OPGB-DIPG002, in presence of LIN (left panel) or BMS (right panel). Results are presented as mean ± SD from 4 donors.