Figure 2.

Change from baseline to trial end in bodyweight according to (a) baseline age subgroup, (b) baseline body mass index (BMI) subgroup, and (c) baseline age and BMI subgroup. *Overall means are based on values from participants across all three treatment arms. Data from the ‘on‐treatment without rescue medication’ observation period in the full analysis set were included in the analysis. The mean change from baseline at the end of the treatment and mean treatment differences (semaglutide – comparator) were estimated using a mixed model for repeated measurements with treatment, subgroup at baseline, and interaction between treatment and subgroup as fixed factors, and the baseline value as covariate, all nested within the visit. BW, body weight; CI, confidence interval; ETD, estimated treatment difference; mono, monotherapy; OAD, oral antidiabetes drug; OW, once weekly.