(A-B) Individual analysis of a silent gonadotroph macroadenoma (SGT-macro, A), and a FCT-macro (FCT4, B) demonstrating the cellular composition, and well-differentiated features of the tumor cells with expression of transcripts associated with secretory function. (C-D) Depiction of the relative similarity in expression of a series of secretory (C) and EMT-associated (D) transcripts in 3 FCT-micros (FCT1-3, blue box), a FCT-macro (FCT4, black box), and a SGT-macro (red box), and their striking difference to expression levels of these transcripts in SCTs (yellow box).