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. 2022 Jul 1;12:23. doi: 10.5334/tohm.698

Table 2.

Disease severity, gait and balance performance, and tremors quantified during the gait and balance tasks comparing between unilateral and bilateral DBS treatment. There were no differences between the two DBS types. Values are shown as mean ± SD. * p < 0.05.


UNILATERAL DBS (N = 10) BILATERAL DBS (N = 7)


OFF ON OFF ON

Stride length variability (CV, %) 2.6 ± 0.5 2.1 ± 0.4 2.4 ± 0.6 2.4 ± 0.6

Sway path length (m/s 2 ) 9.8 ± 6.2 7.0 ± 3.8 9.9 ± 5.9 6.6 ± 2.1

FTM-TRS

        Total 47.8 ± 14.3 28.4 ± 14.9 43.4 ± 9.3 16.0 ± 7.1

        Tremor 13.4 ± 5.0 9.1 ± 5.0 11.2 ± 2.9 7.8 ± 2.4

        Manual 19.6 ± 7.4 12.2 ± 8.0 17.4 ± 6.8 5.5 ± 4.1

        Self 14.8 ± 4.3 7.1 ± 4.6 14.7 ± 2.9 2.5 ± 2.2

TETRAS

        Total 49.1 ± 12.0 27.2 ± 12.4 50.0 ± 5.4 18.1 ± 7.6

        Tremor 8.6 ± 3.2 6.4 ± 3.1 9.0 ± 2.8 6.1 ± 2.8

        Manual 11.3 ± 3.1 7.4 ± 3.0 9.9 ± 2.7 4.4 ± 1.6

        Self 29.2 ± 8.8 13.4 ± 8.5 31.0 ± 5.2 7.5 ± 4.9

Balance tremor (%)

        Upper limb 9.3 ± 5.8 9.1 ± 6.7 6.7 ± 5.2 7.3 ± 4.3

        Lower limb 4.8 ± 3.4 4.5 ± 4.0 7.5 ± 7.8 5.8 ± 3.5

        Upper trunk 7.0 ± 6.6 5.5 ± 4.9 7.0 ± 6.3 4.8 ± 1.2

        Lower trunk 8.6 ± 7.6 6.3 ± 5.2 9.6 ± 7.9 6.1 ± 3.2

Gait tremor (%)

        Upper limb 6.5 ± 2.4 6.3 ± 3.4 7.0 ± 1.9 6.9 ± 2.1

        Lower limb 8.4 ± 2.1 9.1 ± 2.5 9.1 ± 2.1 8.5 ± 2.1

        Upper trunk 5.3 ± 1.3 5.0 ± 1.6 5.6 ± 1.2 5.4 ± 1.2

        Lower trunk 9.0 ± 1.9 9.1 ± 2.1 9.2 ± 1.9 9.5 ± 2.6