Skip to main content
. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: J Bone Miner Res. 2022 Jan 14;37(3):428–439. doi: 10.1002/jbmr.4494

Table 1.

Partial Spearman’s ρ Correlation Coefficients for Association of Individual Parameters With Membership to Each Phenotype

Spearman’s ρ adjusted for membership with other clusters
Healthy phenotype Low density phenotype Low volume phenotype
Age 0.13 0.20 −0.41
Height 0.24 ns −0.23
Weight 0.23 ns −0.08
FN aBMD 0.13 −0.19 0.09
HR-pQCT—Radius
Tt.BMD −0.05 −0.58 0.28
Ct.BMD −0.13 −0.43 0.25
Tb.BMD 0.15 −0.34 −0.04
Tb.N 0.20 −0.22 −0.05
Tb.1/N.SDa 0.15 −0.29 −0.04
Ct.Thd −0.07 −0.51 0.15
Tt.Ar 0.34 0.19 −0.54
Ct.Ar 0.09 −0.47 −0.08
Tb.Ar 0.32 0.26 −0.54
Failure Load 0.31 −0.30 −0.18
HR-pQCT—Tibia
Tt.BMD 0.04 −0.55 0.13
Ct.BMD −0.06 −0.39 0.11
Tb.BMD 0.15 −0.26 −0.09
Tb.N 0.20 −0.14 −0.11
Tb.1/N.SDa 0.17 −0.18 −0.09
Ct.Thd ns −0.49 0.04
Tt.Ar 0.35 0.25 −0.51
Ct.Ar 0.11 −0.46 −0.14
Tb.Ar 0.32 0.32 −0.48
Failure load 0.29 −0.24 −0.26

ns = not significant; FN = femoral neck; aBMD = areal bone mineral density; HR-pQCT = high-resolution peripheral quantitative computed tomography; Tt.BMD = total bone mineral density; Ct.BMD = cortical bone mineral density; Tb.BMD = trabecular bone mineral density; Tb.N = trabecular number; Tb.1/N.SD = trabecular inhomogeneity; Ct.Thd = cortical thickness; Tt.Ar = total cross-sectional area; Ct.Ar = cortical cross-sectional area; Tb.Ar = trabecular cross-sectional area.

All partial correlations shown are statistically significant (p < 0.05) after adjustment for multiple comparisons using the Holm–Bonferroni method.

a

Correlation is inverted to such that a positive correlation reflects a beneficial association between phenotype and the parameter.