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. 2022 Jun 23;6:e2200009. doi: 10.1200/PO.22.00009

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© 2022 by American Society of Clinical Oncology

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FIG 1. — Chronological timeline of diagnostic liver biopsies (red circles), plasma ctDNA assessments (orange triangles), and treatment course of an atypical carcinoid tumor of the lung with TMZ-associated hypermutation treated with checkpoint inhibitor immunotherapy. Included is hematoxylin and eosin staining of histopathologic liver biopsy specimens at 60× magnification. ctDNA, circulating tumor DNA; FOLFIRI, fluorouracil, leucovorin, and irinotecan; FOLFOX, infusional fluorouracil, leucovorin, and oxaliplatin; NA, not available; NET, neuroendocrine tumor; TMZ, temozolomide; WD, well-differentiated.