Figure 3.

LncRNA CASC2 directly targeting miR-155. (a) Sequence alignment of the binding site between lncRNA CASC2 and miR-155. (b) The experiment of the dual-luciferase reporter gene detected the fluorescence activity of lncRNA CASC2-wt/mut under the treatment of miR-155/NC mimics, ^∗∗p < 0.01 vs. group of CASC2-wt + NC mimics. (c) The lncRNA CASC2 expression, preferably after miR-155 mimics/inhibitor transfection, was performed by RT-qPCR, ^∗∗∗p < 0.001 against a group of NC mimics and ^##p < 0.01 against a group of NC inhibitor.