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Changes in the HIF-1α, MMP-2, and TIMP-2 mRNA and protein expression during myopia development. (a) The mRNA level of HIF-1α. (b) The mRNA level of MMP-2. (c) The mRNA level of TIMP-2. (d) The protein levels of HIF-1α. (e) The protein level of MMP-2. (f) The protein level of TIMP-2. ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001.
