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NF-κB inhibitor reversed trophoblast cell proliferation, invasion, and migration induced by LPS. (a) IκBα, p-IκBα, and nucleus NF-κB p65 expressions in trophoblast cells. (b) Cell activity was determined by CCK-8 assay. (c, d) Cell migration and invasion were examined by Transwell assays. (e) Western blot was performed to determine MMP2, MMP9, snail, and E-cadherin levels in trophoblast cells. Scale bar = 100 μm. ∗P < 0.05 vs. control; #P < 0.05 vs. LPS.
