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. 2022 Jun 8;48:101474. doi: 10.1016/j.eclinm.2022.101474

Table 3.

Logistic regression models for incident Parkinson's disease by distressing dream frequency at baseline.

Model PD cases/n OR (95% CI) for Frequent DD vs Non-frequent DD P value
Main analysis
 Age- and Clinic Adjusted Model 91/3818 2·02 (1·2, 3·5) 0·01
 Fully Adjusted Modela 91/3818 2·01 (1·1, 3·6) 0·02
Stratified analysisb
 Baseline to < 5·5 years 30/1438 3·38 (1·3, 8·7) 0·01
 5·5 to 12 years 61/2380 1·55 (0·7, 3·3) 0·26
Sensitivity analysisc 91/3818 1·98 (1·1, 3·6) 0·02

Abbreviations: PD, Parkinson's disease; OR, odds ratio; CI, confidence interval; DD, distressing dreams.

a

Adjusted for age, clinic site, race, education, smoking status, alcohol intake, depression, sleep onset insomnia, sleep maintenance insomnia, diabetes, hypertension, physical activity, self-rated health and medication use.

b

Analysis stratified according to length of follow-up, with adjustment for covariates in the fully adjusted model.

c

Sensitivity analysis further adjusted for anxiety, cognitive function and excessive daytime sleepiness, in addition to covariates in the fully adjusted model.