Table 2.
All Treatment-Related Grade 3–5 Adverse Events (N = 35 patients)
Total | Attributed to Avelumab | Attributed to Trabectedin | Attributed to Both | |||||
---|---|---|---|---|---|---|---|---|
AE Term | Count | % | Count | % | Count | % | Count | % |
Alanine aminotransferase increased | 6 | 18% | 0 | 0% | 6 | 17% | 0 | 0% |
Lymphocyte Count Decreased | 4 | 12% | 1 | 3% | 4 | 11% | 1 | 3% |
Neutrophil count decreased | 3 | 9% | 1 | 3% | 1 | 3% | 1 | 3% |
Anemia | 2 | 6% | 0 | 0% | 2 | 6% | 0 | 0% |
Ejection fraction decreased | 2 | 6% | 0 | 0% | 2 | 6% | 0 | 0% |
Fatigue | 1 | 3% | 0 | 0% | 1 | 3% | 0 | 0% |
Infusion related reaction | 1 | 3% | 1 | 3% | 0 | 0% | 0 | 0% |
Aspartate aminotransferase increased | 1 | 3% | 1 | 3% | 1 | 3% | 0 | 0% |
Port Infection/Inflammation/Erythema | 1 | 3% | 0 | 0% | 1 | 3% | 0 | 0% |
Dyspnea | 1 | 3% | 0 | 0% | 1 | 3% | 0 | 0% |
Gastrointestinal Disorders – Other | 1 | 3% | 0 | 0% | 1 | 3% | 0 | 0% |
White blood cell decreased | 1 | 3% | 0 | 0% | 1 | 3% | 0 | 0% |