TABLE 1.
Characteristicsa of participants stratified by tertile of fat mass to lean body mass ratio.
| RFL |
p | |||
| T1 | T2 | T3 | ||
| RFL | 0.24 (0.18, 0.35) | 0.44 (0.30, 0.51) | 0.59 (0.43, 0.68) | – |
| n (%) | 1066 (33.30) | 1068 (33.36) | 1067 (33.33) | – |
| Female (%) | 563 (52.81) | 564 (52.81) | 563 (52.76) | 1.000 |
| Age (yrs) | 57.89 (50.72, 64.33) | 59.22 (52.22, 65.09) | 61.00 (54.59, 67.06) | <0.001 |
| Mortality (%) | 283 (26.55) | 226 (21.16) | 239 (22.40) | 0.009 |
| Quality of life | 47 (42, 53) | 46 (42, 52) | 46 (42, 52) | 0.009 |
| Nutritional indices | ||||
| Percentage of body fat (%) | 18.20 (14.50, 24.90) | 29.10 (21.80, 32.35) | 35.80 (28.70, 38.80) | <0.001 |
| Fat mass (kg) | 10.44 (8.12, 13.35) | 16.72 (14.56, 19.32) | 23.63 (20.25, 26.94) | <0.001 |
| Lean body mass(kg) | 42.10 (37.40, 48.00) | 43.00 (37.50, 49.65) | 42.30 (36.70, 48.90) | 0.117 |
| Body mass index (kg/m2) | 20.59 (19.14, 22.21) | 23.51 (21.97, 24.88) | 25.85 (24.22, 27.82) | <0.001 |
| Handgrip strength | 22.52 (17.40, 30.20) | 23.80 (18.40, 31.85) | 23.70 (18.00, 31.00) | 0.020 |
| C-reactive protein | 3.29 (3.02, 18.60) | 3.23 (2.31, 13.22) | 3.79 (3.00, 13.10) | 0.154 |
| PG-SGA | ||||
| 0–1 | 422 (13.18) | 525 (16.40) | 560 (17.49) | <0.001 |
| 2–8 | 528 (16.49) | 423 (14.46) | 469 (13.40) | |
| ≥9 | 116 (3.62) | 80 (2.50) | 78 (2.44) | |
| NRS2002 scores (≥ 3,%) | 257 (24.11) | 119 (11.14) | 96 (9.00) | <0.001 |
| KPS scores | 90 (90, 90) | 90 (90, 100) | 90 (90, 100) | 0.009 |
| Nutrition support b (yes,%) | 220 (20.64) | 197 (18.45) | 183 (17.15) | 0.114 |
| Cancer types | ||||
| Lung cancer | 365 (11.40) | 368 (11.50) | 355 (11.09) | <0.001 |
| Breast cancer | 166 (5.19) | 226 (7.06) | 287 (8.97) | |
| Colorectal cancer | 125 (3.91) | 170 (5.31) | 149 (4.65) | |
| Esophageal cancer | 39 (1.22) | 24 (0.75) | 14 (0.44) | |
| Gastric cancer | 32 (1.00) | 40 (1.25) | 46 (1.44) | |
| Others | 339 (10.59) | 240 (7.50) | 216 (6.75) | |
| TNM stages | ||||
| I | 99 (4.01) | 105 (4.25) | 106 (4.29) | 0.888 |
| II | 158 (6.40) | 151 (6.12) | 137 (5.55) | |
| III | 213 (8.63) | 209 (8.46) | 228 (9.23) | |
| IV | 164 (6.64) | 340 (13.78) | 367 (14.87) | |
| Treatments | ||||
| Surgery | 207 (6.47) | 178 (5.56) | 187 (5.84) | 0.001 |
| Chemotherapy | 653 (20.40) | 652 (20.37) | 600 (18.74) | |
| Radiotherapy | 21 (0.66) | 17 (0.53) | 40 (1.25) | |
| Others | 185 (5.78) | 221 (6.90) | 240 (7.50) | |
| Duration of hospital stays (days) | 11.00 (7.00, 19.00) | 11.00 (7.00, 18.00) | 11.00 (7.00, 18.00) | 0.736 |
| Socio-demographics | ||||
| High education level c (%) | 751 (70.45) | 823 (77.06) | 814 (76.29) | 0.001 |
| Smoking (Current,%) | 316 (29.64) | 253 (23.69) | 249 (23.34) | 0.003 |
| Alcohol drinking (yes,%) | 204 (19.14) | 192 (17.98) | 195 (18.28) | 0.774 |
| Tea (yes,%) | 179 (17.26) | 207 (19.38) | 211 (19.78) | 0.158 |
| Family history of cancer (yes,%) | 168 (15.76) | 213 (19.94) | 192 (17.99) | 0.042 |
| Comorbidity (yes,%) | 391 (36.68) | 330 (30.90) | 266 (24.93) | <0.001 |
PG-SGA, patient-generated subjective nutrition assessment; NRS 2002, nutrition risk screening 2002; KPS, Karnofsky performance scores; RFL, ratio of fat mass to lean body mass.
aValues are medians (Q1, Q3) or frequencies. Test for difference between tertiles of fat mass to lean body mass ratio was performed by using Kruskal–Wallis tests for non-normally distributed continuous variables and chi-square test for categorical variables.
bReceive enteral nutrition or parenteral nutrition.
cSchool years ≥ 12 years.