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. 2022 Jun 16;9:914020. doi: 10.3389/fnut.2022.914020

TABLE 2.

Association between fat mass to lean body mass ratio and all-cause mortality using Cox proportional hazard regression.a

<60 years
P for trend ≥60 years
P for trend
T1 T2 T3 T1 T2 T3
Female
Unadjusted model 1 0.77 (0.53, 1.11) 0.72 (0.49, 1.06) 0.172 1 0.84 (0.57, 1.24) 0.74 (0.51, 1.07) 0.282
Model Ab 1 0.79 (0.55, 1.15) 0.69 (0.47, 1.02) 0.159 1 0.95 (0.64, 1.41) 0.83 (0.57, 1.22) 0.624
Model Bb 1 0.99 (0.67, 1.46) 0.84 (0.56, 1.26) 0.661 1 1.07 (0.71, 1.61) 0.96 (0.64, 1.44) 0.857
Model Cb 1 1.04 (0.66, 1.64) 0.95 (0.57, 1.56) 0.935 1 1.30 (0.82, 2.07) 1.10 (0.69, 1.75) 0.521
Model Db 1 0.86 (0.48, 1.54) 0.66 (0.34, 1.30) 0.486 1 2.08 (1.08, 4.01) 0.90 (0.45, 1.81) 0.018
Male
Unadjusted model 1 0.83 (0.59, 1.18) 0.87 (0.60, 1.25) 0.549 1 0.58 (0.42, 0.79) 0.66 (0.50, 0.88) 0.001
Model Ab 1 0.84 (0.59, 1.20) 0.88 (0.61, 1.28) 0.610 1 0.58 (0.43, 0.80) 0.63 (0.47, 0.84) 0.001
Model Bb 1 0.86 (0.60, 1.23) 0.99 (0.67, 1.44) 0.682 1 0.57 (0.42, 0.79) 0.62 (0.46, 0.84) 0.001
Model Cb 1 0.80 (0.51, 1.27) 1.00 (0.64, 1.57) 0.569 1 0.65 (0.45, 0.94) 0.66 (0.46, 0.95) 0.033
Model Db 1 0.98 (0.54, 1.78) 1.25 (0.72, 2.17) 0.653 1 0.74 (0.46, 1.20) 0.84 (0.53, 1.33) 0.475

aValues are models adjusted HR and 95% confidence interval, ranges for tertiles (T) 1 through 3. Linear trends (p for trend) were obtained with the ratio of fat mass to lean body mass as continuous variables.

bModel A: adjusted for age, education, smoking, alcohol drinking, family history of cancer, version of Body Composition Analyzer; Model B: as model A and additionally adjusted for Karnofsky performance scores, duration of hospital stays, NRS 2002 score, nutrition support, and handgrip strength; Model C: as Model B and additionally adjusted for commodities, previous treatments, cancer types, TNM stages, and quality of life; Model D: as Model C and additionally adjusted C-reaction protein.