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. 2022 Mar 6;61(6):847–856. doi: 10.1007/s40262-021-01106-x

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© The Author(s) 2022, corrected publication 2022

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Fig. 1 — Visual predictive check associated with the final population pharmacokinetic model of total concentrations (top) and unbound concentrations (bottom) (x-axes indicated time in hours, and y-axes indicate ceftriaxone concentration in mg/L). Open circles represent the observed data, and the lines represent the 5th, 25th, 50th, 75th, and 95% percentiles of the simulated plasma concentrations (n = 1000)