Table 3.
Optimal cut-off values and diagnostic performance of biomarkers for predicting bacteremia.
| Biomarkers | AUC | Methods | Cut-off point | Sensitivity (%) | Specificity (%) | LR+ | LR– |
|---|---|---|---|---|---|---|---|
| Procalcitonin | 0.80 | Liu | 0.38 ng/mL | 74.1 | 73.7 | 2.82 | 0.35 |
| Youden | |||||||
| Closest-to-(0,1) | |||||||
| Presepsin | 0.69 | Liu | 407 pg/mL | 60.3 | 75.4 | 2.46 | 0.53 |
| Youden | |||||||
| Closest-to-(0,1) | |||||||
| C-reactive protein | 0.60 | Liu | Not detectable | ||||
| Youden | 121 mg/L | 40.0 | 82.5 | 2.26 | 0.73 | ||
| Closest-to-(0,1) | 52.2 mg/L | 56.9 | 57.9 | 1.35 | 0.74 | ||
AUC, area under the curve; LR, likelihood ratio.