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. 2022 Jul 1;12:11200. doi: 10.1038/s41598-022-15234-2

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Association of LGR5 with β-catenin expression in endometrioid carcinomas (ECs). (A) A bar graph showing percentages of nuclear β-catenin expression in various ovarian carcinomas. (B) Representative images of a EC expressing nuclear β-catenin and no LGR5 (EC #1), and a EC expressing normal membranous β-catenin and strong LGR5 (EC #2). Scale bar, 50 µm (C) A table showing the correlations of epithelial or stromal LGR5 with nuclear β-catenin expression in ECs. LGSC, low-grade serous carcinoma (n = 12); HGSC, high-grade serous carcinoma (n = 64); CCA, clear cell carcinoma (n = 48).