Figure 1.

Overview of 36,036 single cells from seven prostate cancers

(A) UMAP of the 36,036 cells profiled in seven patients. Two HSPC, three CRPC, and two pure small cell prostate cancers were depicted here. Different cell types were color-coded. For samples with parallel WES data (P1, P3, and P6), cells with at least one mutant read detected were colored black; P4, P5, and P7 come from published data (GSE137829) (also see Figure S1, S2, Tables S1, S2, and S3, and S5).

(B) Distribution of cancer score in TCGA and CPGEA, respectively (STAR Methods) for cells categorized as malignant or normal, data are represented as boxplot (Wilcoxon rank-sum test, ∗∗∗∗: p ≤ 0.0001) (also see Table S4).