Extended Data Figure 1 |. Platform configurability and modularity.

a, Photograph of the assembled platform. b, Top view of the platform including each compartment chamber and reservoir for circulating media. c, Bottom view of the platform. d, Configurability of the platform can be established through connecting reactors in series for scaling of engineered organs. e, Alternative platform design for single-organ culture with perfusion and vascular barrier. f, Alternative platform design for dual-organ culture with perfusion and vascular barrier. g, Platform with tubing attached to a peristaltic pump during integrated culture. h, Computational fluidic model of shear stress during perfusion with the vascular barrier, at a flow rate of 1.3 mL/min to yield a shear stress of 1.88 dyn/cm² at the vascular barrier interface.