Two case examples illustrating the quality of DWI-EPI distortion correction using the Synb0-DisCo technique. A: patient 11; B: patient 17. Both intraoperative MRI were acquired at the first surgical stage (iMRI1), following cranial opening, prior to corticectomy and lesion resection. Selected orthogonal T1W images, both distortion corrected and uncorrected b0 images are shown in radiological orientation (left, L; right, R). There are visible improvements in the DWI-EPI distortion post correction, at the typically described basal frontal, temporal and occipital regions, the dorsal cerebellar hemisphere and the globe (white arrowheads). There is additional correction of b0 image distortion at and near the metallic skull pin sites (solid white arrows), and over the exposed cortical surface at the craniotomy site (dashed white arrows). [print as a single image].