Mutual information between the FA and T1W images, with and without EPI distortion correction using the Synb0-DisCo technique. A: intraoperative MRI data acquired at the first surgical time point (iMRI1), following cranial opening, prior to corticectomy and lesion resection. B: data acquired at the second surgical time point (iMRI2) following initial lesion resection. The mutual information indices were significantly greater for EPI distortion corrected diffusion data compared to those without correction, at both surgical time points. * p < 0.001 ** p < 0.0001. Abbreviation: intraoperative magnetic resonance imaging, iMRI; mutual information, MI. [print as a single image].