Table 3.
Diagnostic Characteristics of G8 and fTRST for Patients with Cancer (N = 755).
| Measure, cut-off point | Prevalence of frailty (%) (G8/fTRST) |
Prevalence of frailty (%) (CGA) |
Sensitivity (%) (95% CI) |
Specificity (%) (95% CI) |
PPV (%) (95% CI) |
NPV (%) (95% CI) |
YI | C-index (95% CI) |
|---|---|---|---|---|---|---|---|---|
| G8 | ||||||||
| ≤14 | 57.7 | 40.9 | 80.6 (75.7–84.8) | 58.1 (53.3–62.7) | 57.1 (52.3–61.8) | 81.2 (76.5–85.3) | 0.39 | 0.77 (0.74–0.81)∗∗∗ |
| ≤13 | 44.5 | 40.9 | 68.4 (62.9–73.6) | 72.0 (67.6–76.1) | 62.7 (57.3–67.9) | 76.8 (72.5–80.8) | 0.40 | |
| ≤12 | 35.5 | 40.9 | 56.7 (50.9–62.3) | 79.2 (75.1–82.8) | 65.2 (59.1–70.9) | 72.6 (68.4–76.6) | 0.36 | |
| fTRST | ||||||||
| ≥1 | 75.0 | 40.9 | 88.4 (84.2–91.7) | 34.3 (29.9–38.9) | 48.2 (44.1–52.4) | 81.0 (74.6–86.3) | 0.23 | 0.71 (0.67–0.75)∗∗∗ |
| ≥2 | 45.6 | 40.9 | 65.5 (59.9–70.8) | 68.2 (63.6–72.5) | 58.6 (53.2–63.9) | 74.2 (69.6–78.3) | 0.34 | |
| ≥3 | 22.6 | 40.9 | 36.5 (31.1–42.1) | 87.0 (83.5–90.0) | 65.9 (58.2–73.0) | 66.6 (62.6–70.4) | 0.24 | |
∗∗∗p < .001.
NPV, negative predictive value; PPV, positive predictive value; YI, Youden Index.