. Author manuscript; available in PMC: 2022 Jul 2.

Published in final edited form as: Transfusion. 2020 May 1;60(6):1175–1182. doi: 10.1111/trf.15833

Table 2:

Hemoglobin increments after RBC transfusion by smoking status for gamma irradiation and donor sex

	Unirradiated RBC^* (n=4,129)	Irradiated RBC^* (n=957)	Female Donor^† (n=1,852)	Male Donor^† (n=3,234)
Non-smoker RBC units (n=4,760)	n=3,857	n=903	n=1,755	n=3,005
Pre-TX hemoglobin level (SD)	7.71 (0.82)	7.49 (0.73)	7.67 (0.81)	7.68 (0.81)
Post-TX hemoglobin level (SD)	8.74 (1.06)	8.43 (1.01)	8.64 (1.06)	8.72 (1.06)
Hemoglobin Increment (SD)	1.03 (0.92)	0.94 (0.83)	0.97 (0.92)	1.05 (0.90)
Smoker RBC units (n=326)	n=272	n=54	n=97	n=229
Pre-TX hemoglobin level (SD)	7.78 (0.90)	7.57 (0.72)	7.72 (0.93)	7.76 (0.86)
Post-TX hemoglobin level (SD)	8.83 (1.17)	8.30 (1.07)	8.83 (1.19)	8.74 (1.17)
Hemoglobin Increment (SD)	1.05 (0.98)	0.74 (0.80)	1.11 (0.96)	0.98 (0.95)

RBC=red blood cell; TX=transfusion

P-values for t-test comparing hemoglobin increments for transfusion of gamma-irradiated RBC units from donor smokers to those for unirradiated RBC units from smokers (p=0.045), gamma-irradiated RBC units from donor non-smokers to those for unirradiated RBC units from non-smokers (p=0.02), unirradiated RBC units from donor smokers and non-smokers (p=0.80), and irradiated RBC units from donor smokers and non-smokers (p=.074).

^†

Hemoglobin increments did not differ between donor smokers and non-smokers when examining subgroups of RBC units donated by male and female donors (p=0.23 and 0.14, respectively).