Table 2.
Genotype, allele frequency, and phenotype of Vitamin D Binding Protein gene in diabetic patients with and without retinopathy
| Diabetic mellitus with retinopathy (N = 59) | Diabetic mellitus without retinopathy and/or nephropathy (N = 81) | P-value | |
|---|---|---|---|
| Genotype- rs4588 | |||
| CC (Thr/Thr) | 54.2%(32) | 64.2%(52) | 0.4 |
| AA (Lys/Lys) | 6.8%(4) | 6.2%(5) | |
| AC (Lys/Thr) | 39.0%(23) | 29.6%(24) | |
| Genotype- rs7041 | |||
| TT (Asp/Asp) | 8.5%(5) | 8.6%(7) | 0.9 |
| GG (Glu/Glu) | 37.3%(22) | 38.3%(31) | |
| TG (Asp/Glu) | 54.2%(32) | 53.1%(43) | |
| allele Freq. rs4588 | |||
| C | 0.74 | 0.75 | 0.3 |
| A | 0.26 | 0.25 | |
| allele Freq.rs7041 | |||
| T | 0.29 | 0.29 | 0.3 |
| G | 0.71 | 0.71 | |
| GC phenotype | |||
| Gc1f, Gc1f | 1.7%(1) | 1.2% (1) | 0.7a |
| Gc1s, Gc1s | 37.3%(22) | 38.3%(31) | |
| Gc2, Gc2 | 1.7%(1) | 1.2%(1) | |
| GC1f,GC1s | 15.3%(9) | 24.7%(20) | |
| GC1f,GC2 | 6.8%(4) | 7.4%(6) | |
| GC1s,GC2 | 37.3%(22) | 27.2%(22) | |
afisher’s exact test