Table 4.
Hepatic blood flow & pressure measurements
| Variable | Timepoint | Total Group (n = 28) |
Group S (n = 20) |
Group NS (n = 8) |
|---|---|---|---|---|
|
Total HBF indexed (ml min−1 m−2) |
T1 | 548 (182) | 511 (168) | 640 (191) |
| T2 | 465 (149)# | 447 (153) # | 508 (138)# | |
| T3 | 458 (144)# | 454 (145) # | 467 (149)# | |
|
Relative Total HBF (% of CO) |
T1 | 17.8 (5.7) | 16.7 (5.6) | 20.4 (5.4) |
| T2 | 15.2 (4.6)# | 14.7 (4.9) # | 16.3 (3.8) # | |
| T3 | 14.6 (4.3)# | 14.6 (4.5) # | 14.7 (4.0)# | |
|
HAF indexed (ml min−1 m−2) |
T1 | 215 (118) | 216 (128) | 212 (95) |
| T2 | 163 (83)# | 162 (82)# | 164 (92)# | |
| T3 | 142 (70)# | 150 (79)# | 124 (41)# | |
|
Relative HAF (% of CO) |
T1 | 6.9 (3.6) | 7.0 (3.9) | 6.8 (3.0) |
| T2 | 5.3 (2.7)# | 5.3 (2.5)# | 5.3 (2.9)# | |
| T3 | 4.6 (2.3)# | 4.8 (2.6)# | 3.9 (1.3)# | |
|
Conductance HAF (ml min−1 m−2 mmHg−1) |
T1 | 3.0 (1.8) | 3.0 (1.9) | 3.0 (1.4) |
| T2 | 1.9 (1.0)# | 1.9 (0.9)# | 2.0 (1.1)# | |
| T2 | 1.6 (0.8)# | 1.6 (0.9)# | 1.3 (0.4)# | |
|
PVF indexed (ml min−1 m−2) |
T1 | 333 (137) | 295 (109)* | 429 (161)* |
| T2 | 302 (117) | 285 (109) | 344 (133)# | |
| T3 | 315 (120) | 304 (109) | 344 (151)# | |
|
Relative PVF (% of CO) |
T1 | 10.9 (4.5) | 9.8 (4.0)* | 13.7 (4.8)* |
| T2 | 9.9 (3.7) | 9.4 (2.5) | 11.1 (3.8)# | |
| T3 | 10.0 (3.5) | 9.7 (3.3) | 10.8 (4.2)# | |
|
Portal Pressure (mmHg) |
T1 | 10 (5) | 9 (5) | 11 (5) |
| T2 | 11 (5) | 10 (5) | 12 (5) | |
| T3 | 10 (5) | 9 (5) | 12 (6) | |
|
Caval Pressure (mmHg) |
T1 | 7 (4) | 6 (3) | 8 (4) |
| T2 | 6 (4) | 6 (4) | 6 (4) | |
| T3 | 7 (4) | 7 (4) | 6 (4) | |
| PI Portal Vein | T1 | 0.6 (0.4) | 0.7 (0.5) | 0.5 (0.3) |
| T2 | 1.2 (2.3) | 1.4 (2.7) | 0.7 (0.4) | |
| T3 | 0.6 (0.3) | 0.6 (0.3) | 0.6 (0.3) | |
| PI Hepatic Artery | T1 | 1.2 (0.5) | 1.3 (0.6) | 1.0 (0.4) |
| T2 | 1.5 (0.5) | 1.6 (0.5) | 1.4 (0.5) | |
| T3 | 1.5 (0.7) | 1.6 (0.6) | 1.4 (0.8) |
Data are expressed in mean (SD)
HBF Hepatic Blood Flow, HAF Hepatic Arterial blood Flow, PVF Portal Vein blood Flow, PI Pulsatility Index
Significant differences are marked as * for significant between group difference and # for significant within group difference, compared to T1 (p < 0.05)