Table 1.
Weight, Serum Parameters in Each Group
| Parameter | Sham | AMI+Vehicle | AMI+DAPA Low | AMI+DAPA Med | AMI+DAPA High |
|---|---|---|---|---|---|
| Weight, g | 377.50±31.51 | 391.08±28.87 | 346.83±27.94 | 372.99±37.67 | 357.75±16.68 |
| Cr, mmol/L | 51.76±18.60 | 37.81±13.31 | 43.10±6.37 | 42.10±11.94 | 44.10±10.06 |
| BUN, mg/dl | 19.37±2.92 | 19.46±1.62 | 28.89±1.94*# | 24.68±3.58*# | 28.99±3.40*# |
| Glu, mmol/L | 9.44±2.15 | 11.71±2.38 | 4.90±0.83*# | 5.64±1.32*# | 5.17±0.72*# |
| K+, mmol/L | 4.19±0.16 | 3.98±0.15 | 4.08±0.61 | 4.18±0.38 | 4.19±0.48 |
| Na+, mmol/L | 138.13±9.78 | 143.34±7.12 | 133.23±6.39 | 141.82±9.08 | 138.65±4.40 |
| Ca2+, mmol/L | 2.50±0.04 | 2.35±0.08* | 2.49±0.02# | 2.45±0.08# | 2.52±0.02# |
| P, mmol/L | 2.73±0.30 | 2.30±0.12 | 2.75±0.39 | 2.46±0.36 | 2.60±0.24 |
Notes: *P < 0.05 vs Sham; #P < 0.05 vs AMI + Vehicle; n=5-9 for each group.
Abbreviations: AMI, acute myocardial infarction; BUN, blood urea nitrogen; Cr, creatinine; DAPA, dapagliflozin; Glu, glucose; Med, medium; P, phosphorus.