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. Author manuscript; available in PMC: 2022 Jul 2.
Published in final edited form as: Cell Rep. 2022 May 24;39(8):110840. doi: 10.1016/j.celrep.2022.110840

Figure 1. HIV-1 IN interacts with FANCI and FANCD2.

Figure 1.

(A) Schematic domain organization of HIV-1 IN.

(B) 293A cells were stably transduced with empty lentiviral vector (−) or lentiviral vector expressing FLAG-tagged full-length HIV-1 IN (+). Cell lysates were treated with benzonase. FLAG-tagged IN was immunoprecipitated by anti-FLAG antibody. The co-immunoprecipitated FANCI and FANCD2 were probed by western blot.

(C) 293A cells were stably transduced with empty lentiviral vector (−) or lentiviral vector expressing flag-tagged CTD of HIV-1 IN (+). Cell lysates were treated with benzonase. FLAG-tagged IN CTD was immunoprecipitated by anti-FLAG antibody. The co-immunoprecipitated FANCI and FANCD2 were probed by western blot.

See also Figure S1.