Table 3.
List and values of different selected parameters used for calculation drug likeliness properties of molecules.
Sr No. | Parameters | Ebselen | Nalsudaldain | Rhamnezine | Galangin |
---|---|---|---|---|---|
1. | HB Donor | 0 | 1 | 2 | 2 |
2. | HB Acceptor | 3.5 | 7.75 | 5.25 | 3.75 |
3. | LogPO/W | 4.285 | 3.193 | 2.146 | 1.769 |
4. | logBB | −0.150 | −0.494 | −1.284 | −1.195 |
5. | % Human oral Absorption | 100 | 100 | 83.204 | 78.385 |
6. | PSA | 56.725 | 94.639 | 108.768 | 94.832 |
7. | Ro5 Violation | 0 | 0 | 0 | 0 |
8. | Ro3 Violation | 0 | 1 | 0 | 0 |
9. | Molecular Weight | 334.39 | 418.39 | 330.29 | 270.24 |