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. 2022 Jun 28;14:1203–1211. doi: 10.2147/NSS.S361529

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© 2022 Tufik et al.

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Relationship between OSA and IgG anti-SARS-CoV-2. (A) Association of reactive IgG results with OSA severity groups (X²=0.912; p=0.634), presented as percentage of seropositive (reactive) or seronegative (non-reactive) results out of each OSA severity group. (B) Spearman correlation indexes between IgG levels and AHI (scatter plot) and other respiratory variables (table). The horizontal axis was divided in two segments for a better visualization of data. (C) Box plot comparing IgG levels among all OSA severity groups (one-way ANOVA with Welch’s correction, F_(2;73.7): 0.505, p=0.606). The box represents median and IQR, the whiskers represent minimum and maximum, and the isolated dots represent outliers. The vertical axis was divided in two segments for a better visualization of data. (D) Histograms disclosing IgG levels frequencies among all OSA severity groups (two records were excluded from the severe OSA group, at 18,633.50 and 31,763.50 AU/ML).

Abbreviations: AHI, apnea-hypopnea index; IgG, immunoglobulin G; IGR, Interquartile range; OSA, obstructive sleep apnea; RDI, respiratory disorder index; SpO2 av, average percutaneous oxygen saturation; SpO2 min, minimum SpO2; SpO2<90%, percentage of SpO2<90% out of the total sleep time.