Table 2.
Mean values of clinical variables at the pre-treatment, immediately post-treatment, and 6 months after treatment (Standard Deviation in parentheses); results of one-way ANOVAs for group effects before treatment
| Group Variable |
M1 | DLPFC | OIC | Sham | Baseline difference | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pre mean (SD) n = 34 |
Post mean (SD) n = 29 |
6 months mean (SD) n = 24 |
Pre mean (SD) n = 33 |
Post mean (SD) n = 26 |
6 months mean (SD) n = 23 |
Pre mean (SD) n = 33 |
Post mean (SD) n = 28 |
6 months mean (SD) n = 24 |
Pre mean (SD) n = 30 |
Post mean (SD) n = 25 |
6 months mean (SD) n = 21 |
One-way ANOVA | ||||
| F | p | |||||||||||||||
| FSQ | 21.03 (4.55) | 18.04 (6.40) | 19.08 (6.38) | 20.67 (5.18) | 18.62 (6.72) | 16.96 (6.53) | 21.00 (4.72) | 17.21 (6.84) | 17.92 (6.52) | 21.47 (5.64) | 18.28 (5.81) | 18.65 (6.50) | 0.133 | 0.94 | ||
| SSS | 9.09 (1.92) | 8.53 (2.51) | 8.40 (2.47) | 9.30 (2.39) | 7.44 (2.50) | 7.92 (2.58) | 9.45(1.75) | 7.25 (2.30) | 8.04 (2.44) | 8.93 (2.78) | 7.64 (2.77) | 8.17 (2.87) | 0.332 | 0.80 | ||
| WPI | 11.93 (3.67) | 9.50 (4.75) | 11.13 (4.53) | 11.36 (3.87) | 10.89 (6.15) | 9.40 (4.65) | 11.54 (4.17) | 9.96 (5.67) | 9.88(4.71) | 12.53 (4.44) | 10.64 (4.48) | 10.47 (4.96) | 0.512 | 0.68 | ||
| SF-36 Mean | 34.91 (13.86) | 42.13 (17.34) | 42.43 (18.84) | 37.76 (13.63) | 45.15 (15.07) | 46.78 (13.95) | 35.69 (13.48) | 44.22 (14.82) | 46.09 (18.64) | 32.96 (13.13) | 41.35 (16.05) | 40.86 (20.41) | 0,679 | 0.57 | ||
| Physical Function | 43.13 (23.37) | 42.93 (24.04) | 48.12 (25.074) | 44.854 (19.34) | 46.92 (18.92) | 55.83 (17.05) | 40.61 (19.87) | 43.39 (17.69) | 47.29 (24.93) | 40.50 (17.19) | 45.40 (18.25) | 50.45 (19.89) | 0.313 | 0.82 | ||
| Physical Role | 26.95 (19.86) | 35.48 (21.23) | 41.41 (25.39) | 33.33 (21.63) | 35.27 (24.67) | 39.84 (25.59) | 26.51 (19.14) | 42.00 (22.08) | 45.31 (26.02) | 25.42(21.06) | 36.12 (26.02) | 39.77 (29.54) | 0.995 | 0.40 | ||
| Body Pain | 22.81 (14.44) | 28.93 (20.64) | 29.92 (23.13) | 22.73 (15.50) | 30.38 (20.76) | 31.58 (16.62) | 22.76 (16.68) | 35.57 (19.68) | 30.83 (18.15) | 19.73 (16.18) | 28.40 (17.35) | 27.54 (20.90) | 0.285 | 0.84 | ||
| General Health | 30.66 (18.66) | 32.79 (21.02) | 32.50 (20.16) | 31.58 (17.80) | 34.35 (19.39) | 39.33 (16.93) | 29.31 (14.58) | 30.93 (13.73) | 34.21 (17.61) | 27.87 (16.18) | 29.48 (15.74) | 28.27 (18.64) | 0.287 | 0.84 | ||
| Vitality | 23.91 (13.18) | 30.17 (17.70) | 31.46 (17.16) | 26.52 (14.06) | 32.69 (18.55) | 33.75 (18.01) | 26.36 (13.36) | 33.04 (13.08) | 34.17 (16.40) | 23.66 (13.95) | 30.20 (19.55) | 29.32 (18.534) | 0.404 | 0.75 | ||
| Social Function | 40.63 (21.53) | 50.00 (30.07) | 47.40 (28.55) | 44.32 (25.79) | 54.32 (25.97) | 55.73 (21.17) | 37.12 (25.67) | 50.45 (20.83) | 55.21 (28.77) | 36.67 (22.97) | 48.50 (27.56) | 46.02 (30.47) | 0.704 | 0.552 | ||
| Mental Health | 39.87 (15.82) | 49.79 (17.59) | 47.17 (18.69) | 37.21 (15.51) | 53.23 (17.66) | 48.00 (17.01) | 42.91 (13.87) | 52.00 (16.47) | 51.50 (15.84) | 40.40 (14.57) | 47.68 (17.81) | 45.27 (20.45) | 0.804 | 0.49 | ||
| Emotional Role | 51.30 (27.85) | 66.95 (24.55) | 61.46 (31.93) | 61.87 (29.54) | 74.04 (23.25) | 70.14 (25.53) | 54.04 (27.73) | 66.37 (31.71) | 71.18 (29.89) | 49.44 (28.19) | 65.00 (29.76) | 60.23 (30.42) | 1.198 | 0.31 | ||
| FIQ-R total | 70.65 (16.39) | 56.27 (23.68) | 56.15 (22.21 | 63.84(15.36) | 50.73 (22.14) | 54.69 (16.68) | 68.01 (20.77) | 49.99 (24.7) | 54.46 (28.67) | 67.68 (19.05) | 53.75 (23.30) | 54.80 (24.41) | 0.774 | 0.51 | ||
| FIQ-R Symptoms | 37.63 (7.88) | 29.12 (11.18) | 29.96 (10.62) | 35.27 (8.26) | 26.50 (10.72) | 30.50 (9.53) | 35.51 (9.93) | 25.41 (12.21) | 29.98 (16.50) | 36.98 (8.70) | 27.66 (11.79) | 30.70 (11.54) | 0.544 | 0.65 | ||
| FIQ-R Impact | 13.18 (4.71) | 10.97 (6.04) | 10.12 (6.41) | 11.03 (5.19) | 9.54 (6.22) | 8.54 (5.36) | 12.72 (5.74) | 9.00 (6.59) | 9.31 (6.32) | 12.57 (5.76) | 10.08 (6.56) | 9.77 (7.14) | 0.996 | 0.40 | ||
| FIQ-R Function | 19.83 (5.79) | 16.18 (8.33) | 16.07 (7.22) | 17.45 (6.01) | 14.69 (7.69) | 15.65 (6.04) | 19.77 (6.61) | 15.58 (7.61) | 15.17 (8.17) | 18.13 (6.23) | 16.01 (6.94) | 16.31 (7.31) | 1.21 | 0.31 | ||
Mean values were calculated from the available data, with no imputation for missing values. The number of participants at each assessment time varied due to attrition at different stages of the study