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Cohort of patients who initially presented with one autoantibody, and during their condition lost their initial SSc specific Ab, and gained a different one (“switch patients”).
| Antibody lost | Antibody gained | Change in clinical phenotype |
|---|---|---|
| ARA | PmScl | No |
| U3RNP | U1RNP | ILD |
| ATA | ARA | ILD progression |
| U3RNP | Ku | Myositis |
The clinical change is also documented.
