1.
Resource table
| Unique stem cell lines identifier | 1) SCVIi039-A |
|---|---|
| 2) SCVIi040-A | |
| 3) SCVIi041-A | |
| Alternative name(s) of stem cell lines | |
| Institution | Stanford Cardiovascular Institute, Stanford, CA, USA |
| Contact information of distributor | Joseph C. Wu |
| joewu@stanford.edu | |
| Type of cell lines | iPSC |
| Origin | Human |
| Additional origin info required | SCVIi039-A: 74 y/o male, Caucasian SCVIi040-A: 76 y/o male, Caucasian SCVIi041-A: 48 y/o female, Caucasian |
| Cell Source | Blood-isolated peripheral blood mononuclear cells (PBMCs) |
| Clonality | Clonal |
| Method of reprogramming | Sendai virus vector |
| Evidence of the reprogramming transgene loss (including genomic copy if applicable) | RT-qPCR |
| Type of Genetic Modification | N/A |
| Cell culture system used | Feeder-free cell culture |
| Associated disease | Dilated cardiomyopathy (DCM) |
| Gene/locus | LMNA mutation p.Arg133Gln (c.398 G > A) |
| Date archived/stock date | November 12th, 2021 |
| Cell line repository/bank | |
| Ethical approval |
https://hpscreg.eu/cell-line/SCVIi039-A https://hpscreg.eu/cell-line/SCVIi040-A https://hpscreg.eu/cell-line/SCVIi041-A The generation of the lines was approved by the Administrative Panel of Human Subjects Research under IRB #29904 “Derivation of Human Induced Pluripotent Stem Cells (Biorepository)”. |