Table 2.

PheDAS regression results for the primary and confounded PheCodes in the synthetic dataset

	PheCode	Phenotype	Actual LORa	Reg A		Reg B
				LORa	p-valb	LORa	p-valb
Primary	338.2	Chronic pain	1.50	1.500	**	1.490	**
	340	Migraine	1.10	1.099	**	1.128	**
	1011	Complications of surgical and medical procedures	0.70	0.700	**	0.700	**
	296.22	Major depressive disorder	0.60	0.600	**	0.579	**
	530.11	GERD	0.30	0.300	**	0.302	**
	401	Hypertension	0.25	0.249	**	0.257	**
	041	Bacterial infection NOS	−0.20	−0.200	**	−0.194	**
	1009	Injury, NOS	−0.60	−0.599	**	−0.604	**
	495	Asthma	−1.00	−1.000	**	−0.991	**
Confounded	174.1	Breast cancer [female]	0.66 / 0.00c	0.662	**	0.004	-
	292.2	Mild cognitive impairment	−0.2	−0.199	**	−0.500	-

^alog odds ratio

^bsignificant after Bonferroni correction (**), insignificant (−)

^cmale + female log odds ratio / female-only log odds ratio