TABLE 4.
Summary of biological sample and data requests for NIA‐LOAD family‐based study
| Sample requests | N |
| Number of researchers approved for specimens from NCRAD | 56 |
| Number of DNA samples distributed from NCRAD | 67,626 |
| Inclusion in independent efforts | |
| DNA samples in the ADSP White, non‐Hispanic | 27 families; 142 individuals |
| DNA samples in the ADSP Caribbean Hispanic | 31 families; 186 individuals |
| Independently approved researchers for sequencing (WES or WGS) | 421 families; 1655 individuals |
| Approved data requests | |
| dbGaP‐phs000160.v1.p1 (NIA‐LOAD linkage) | 228 |
| dbGaP‐phs000168.v2.p2 (NIA‐LOAD GWAS) | 321 |
| dbGaP‐phs000372.v1.p1 (ADGC & NIA‐LOAD GWAS) | 101 |
| dbGaP‐phs0001572.v7.p4 (ADSP & NIA‐LOAD WGS/WES) | 166 |
| dbGaP‐phs000126.v1.p1 (controls for PD case‐control) | 268 |
| Special analysis group data requests to the ADGC & NIA‐LOAD | 145 |
| NIA Genetics of Alzheimer's Disease Data Storage Site (NIAGADS) | |
| (NG00032, NG00020, NG00033, NG00039, NG00027, NG00015, NG00081, NG00062, NG00036, NG00041, NG00048, NG00058, NG00065, NG00075, NG00076, NG00078, NG00100, NG00067, NG00091) | 111 |
Abbreviations: ADGC, Alzheimer's Disease Genetics Consortium; ADSP, Alzheimer's Disease Sequencing Project; GWAS, genome wide association study; NCRAD, National Centralized Repository for Alzheimer's Disease and Related Dementias; NIA‐LOAD FBS, National Institute on Aging Late‐Onset Alzheimer's Disease Family Based Study; WES, whole exome sequencing; WGS, whole genome sequencing.