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. Author manuscript; available in PMC: 2023 Jul 1.
Published in final edited form as: Prog Retin Eye Res. 2022 Jan 4;89:101039. doi: 10.1016/j.preteyeres.2021.101039

Figure 13. VIP dampens neutrophil infiltration in NL and diabetic healing corneas.

Figure 13.

NL (NW), pretreated with VIP1Ra (NW1VIP1Ra), and diabetic (DMW), pretreated with recombinant VIP (DMW1VIP), mouse corneas were wounded by epithelium debridement (2-mm diameter). Healing corneas collected at 22 hpw from NL and diabetic mice were subjected to WMCM using Ly6G-FITC antibody for mouse neutrophil staining. The images of the whole cornea were captured (A), the marked areas of whole corneas were amplified (B), and central areas were shown (C). (D): Cell numbers in the whole corneas (A) were calculated with ImageJ and presented (mean 6 SD; n 5 3). *P>0.05 (one-way ANOVA). This figure was originally published in (Zhang et al., 2020a).