Skip to main content
. Author manuscript; available in PMC: 2022 Oct 24.
Published in final edited form as: Nat Biomed Eng. 2022 Jan 3;6(10):1167–1179. doi: 10.1038/s41551-021-00810-0

ED Fig. 1. Effect of CORT releasing JTAs on animal physiology over time.

ED Fig. 1

(a) The JTA dissolution-controlled release system was surrounded by an outer JTA to stabilize it on the rat patellar tendon and enable a depot-based delivery system. (b) Rat body weight was examined over time. Data shown as mean ± s.d., as analyzed by ANOVAs, with post hoc tests with Bonferroni corrections. a: P = 0.0008, b: P = 0.002; c: P = 0.006; d: P = 0.0011. N=4–6 rats/group. (c) Blood glucose levels were evaluated over time. Data shown as mean ± s.d., as evaluated by a one-way ANOVA, with post hoc Tukey Tests for multiple comparisons. N=4–6 rats/group. (d) The effect of injury, JTA, and CORT on corticosterone levels 2 days and 14 days post-implantation. Data shown as mean ± s.d., as analyzed by a two-way repeated ANOVA (time and treatment), with post hoc Tukey Tests for multiple comparisons. N=4–6 samples/group.