Table 1.
Characteristics of Patients Enrolled on NSABP B-18, B-27, B-40, and B-41 (N=4654)
| Characteristic | B-18 (n=742) | B-27 (n=2254) |
B-40 (n=1154) | B-41 (n=504) |
|---|---|---|---|---|
| Age, median (range) years | 49 (25-75) | 48 (25-75) | 49 (24-72) | 49 (18-73) |
| Node-positive at entry, n (%) | 201 (27·1%) | 705 (30·1%) | 534 (46·3%) | 252 (50·0%) |
| Clinical tumor size, median (range) cm |
3 (0·9-10·5) | 4 (0·1-25·4) | 4.5 (2-17·5) | 4 (2-20) |
| HR-positive, n (%) | N/A | N/A | 688 (59·6%) | 317 (62·9%) |
| Mastectomy, n (%) | 236 (31·8%) | 864 (37·3%) | 610 (52·9%) | 245 (48·6%) |
| pCR breast, n (%) | 86 (12·9%) | 398 (17·5%) | 356 (30·8%) | 277 (55·0%) |
| pCR node, n (%) | 434 (59·0%) | 1210 (53·7%) | 603 (53·8%) | 386 (77·5%) |
Abbreviations: HR, hormone receptor; NSABP, National Surgical Adjuvant Breast and Bowel Project; pCR, pathological complete response; N/A, not available