Table 2.
Characteristics of Patient Population Enrolled on NSABP B-40 and B-41 by Receipt of RNI (N=1542)
| Characteristic | Received RNI (n=783) | Did not receive RNI (n=759) |
P value |
|---|---|---|---|
| Age, median (range) years | 49 (25-73) | 49 (24-72) | 0·529 |
| Node-positive at entry, n (%) | 484 (61·8%) | 270 (35·6%) | <0·001 |
| Clinical tumor size, median (range) cm | 5 (2-17·5) | 4 (2-20) | <0·001 |
| Race, n (%) | 0·745 | ||
| White | 654 (84·3%) | 630 (84·9%) | |
| Black | 97 (12·5%) | 93 (12·5%) | |
| Other | 25 (3·2%) | 19 (2·6%) | |
| Ethnicity, n (%) | 0·045 | ||
| Hispanic | 73 (9·6%) | 96 (13.1%) | |
| Non-Hispanic | 684 (90·4%) | 639 (86·9%) | |
| HR-positive, n (%) | 514 (65·6%) | 427 (56·3%) | <0·001 |
| Mastectomy, n (%) | 419 (53·5%) | 338 (44·5%) | 0·001 |
| pCR breast, n (%) | 254 (32·4%) | 313 (41·2%) | <0·001 |
| pCR node, n (%) | 356 (45·9%) | 542 (73·7%) | <0·001 |
Abbreviations: HR, hormone receptor; NSABP, National Surgical Adjuvant Breast and Bowel Project; pCR, pathological complete response