Table 3:

Associations of RA-related autoantibodies with isolated RA-bronchiectasis

RA-related autoantibody status*	Multivariable†OR for isolated RA-BR (95%CI)	p-value
RF negative	1.00 (Ref)
RF positive (>1x ULN)	4.40 (2.14-9.07)	<0.0001
RF negative	1.00 (Ref)
RF low-positive (>1-3x ULN)	1.95 (0.67-5.66)	0.22
RF high-positive (>3x ULN)	5.44 (2.57-11.54)	<0.0001
Anti-CCP negative	1.00 (Ref)
CCP positive (>1x ULN)	3.47 (1.65-7.31)	0.001
Anti-CCP negative	1.00 (Ref)
Anti-CCP low-positive (>1-3x ULN)	1.45 (0.29-7.32)	0.65
Anti-CCP high-positive (>3x ULN)	3.73 (1.76-7.90)	0.0006

^*RF analyses included 53 cases and 352 controls (n=12 missing RF status); anti-CCP analyses included 44 cases and 320 controls (n=53 missing anti-CCP status)

^†Adjusted for age, sex, race, RA duration, smoking status, pack-years, and body mass index anti-CCP = anti-cyclic citrullinated peptide; BR = bronchiectasis; CI = confidence interval; OR = odds ratio; RA = rheumatoid arthritis; RF = rheumatoid factor; ULN = upper limit of normal