Table 1.
Dose group (Gy)(MacVittie et al28) | Dose range (Gy)median (min-max range) | Number of animals (% male) | Current age (y) median (min-max range) | Age at irradiation (y) median (min-max range) | Age at arrival (y) median (min-max range) | Median follow-up time since arrival (y) | Number of animals with cancer | Number of cancers | Age at first cancer observation (y) median (min-max range) |
---|---|---|---|---|---|---|---|---|---|
| |||||||||
Control (0) | 0 | 51 (92) | 15.6 (6.8–23.2) | NA | 7.0 (2.4–20.0) | 6.0 | 1 | 1 | 11.5 |
<LD10 (0.01–5.49) | 4.0 (1.14–5.0) | 59 (62) | 7.5 (5.1–14.9) | 5.0 (2.7–8.2) | 4.9 (2.6–10.3) | 3.9 | 7 | 7 | 11.8 (6.4–14.9) |
LD10-50 (5.5–6.74) | 6.5 (5.5–6.73) | 79 (77) | 5.0–23.1 (10.1) | 4.6 (2.3–15.5) | 5.2 (2.6–16.0) | 3.9 | 16 | 19 | 11.0 (5.0–23.1) |
LD50-90 (6.75–7.99) | 6.8 (6.75–7.85) | 87 (66) | 2.7–19.2 (7.9) | 3.9 (2.3–7.0) | 4.9 (2.6–9.9) | 3.3 | 17 | 29 | 9.7 (5.2–17.8) |
LD90+ (>8.0) | 8.1 (8–8.5) | 14 (93) | 3.8–19.2 (10.3) | 3.7 (3.2–5.1) | 4.2 (3.5–5.5) | 6.2 | 4 | 6 | 10.2 (9.8–11.0) |
Abbreviation: LD = lethality dose.