Table 2:
Crude and adjusted linear regression models of isoflavones, lignans and total phytoestrogens intake during puberty up to 2 year after menarche onset and %FGV and AFGV at 2 years after menarche onset
| AFGV (cm3) | %FGV | |
|---|---|---|
| β (95%CI) | β (95%CI) | |
| Isoflavones | ||
| Model 1 | ||
| 1st quartile | ref | ref |
| 2nd quartile | −9.11 (−33.24, 15.02) | −2.05 (−6.67, 2.57) |
| 3rd quartile | −15.58 (−39.05, 7.89) | 2.02 (−2.47, 6.51) |
| 4th quartile | −21.88 (−45.83, 2.08) | 1.80 (−2.79, 6.38) |
| Model 2 | ||
| 1st quartile | ref | ref |
| 2nd quartile | −17.32 (−43.98, 9.34) | −1.16 (−5.08, 2.76) |
| 3rd quartile | −22.48 (−51.12, 6.16) | −0.20 (−4.41, 4.00) |
| 4th quartile | −29.13 (−59.37, 1.11) | −1.24 (−5.68, 3.20) |
| Model 3 | ||
| 1st quartile | ref | ref |
| 2nd quartile | −17.85(−44.50, 8.80) | −1.42 (−5.31, 2.47) |
| 3rd quartile | −21.66 (−50.30, 6.98) | −0.62 (−4.80, 3.56) |
| 4th quartile | −30.54 (−60.66; −0.42)* | −1.53 (−5.92, 2.87) |
| Lignans | ||
| Model 1 | ||
| 1st quartile | ref | ref |
| 2nd quartile | −11.31 (−40.41, 17.80) | 0.39 (−5.19, 5.96) |
| 3rd quartile | −17.63 (−39.43, 4.17) | 1.86 (−2.32, 6.03) |
| 4th quartile | −4.87 (−27.26, 17.51) | 2.80 (−1.49, 7.08) |
| Model 2 | ||
| 1st quartile | ref | ref |
| 2nd quartile | −8.01 (−38.50, 22.49) | −0.57 (−5.04, 3.89) |
| 3rd quartile | −16.71 (−41.20, 7.78) | −0.78 (−4.36, 2.81) |
| 4th quartile | −4.52 (−29.79, 20.75) | 0.80 (−2.90, 4.50) |
| Model 3 | ||
| 1st quartile | ref | ref |
| 2nd quartile | −8.58 (.39.18, 22.01) | −0.44 (−4.88, 4.00) |
| 3rd quartile | −16.86 (−41.49, 7.77) | −1.19 (−4.77, 2.38) |
| 4th quartile | −3.08 (−28.49, 22.33) | 0.69 (3.00, 4.37) |
| Total Phytoestrogens | ||
| Model 1 | ||
| 1st quartile | ref | ref |
| 2nd quartile | −11.36 (−35.60, 12.89) | 0.97 (−3.70, 5.64) |
| 3rd quartile | −8.69 (−31.75, 14.37) | −0.68 (−5.12, 3.75) |
| 4th quartile | −27.93 (−52.09, −3.78)* | 1.92(−2.73, 6.57) |
| Model 2 | ||
| 1st quartile | ref | ref |
| 2nd quartile | −17.39 (−44.64, 9.87) | 0.11 (−3.90, 4.13) |
| 3rd quartile | −16.98 (−44.50, 10.53) | −1.93 (−5.98, 2.12) |
| 4th quartile | −37.31 (−67.20, −7.42)* | −1.03 (−5.43, 3.37) |
| Model 3 | ||
| 1st quartile | ref | ref |
| 2nd quartile | −17.30 (−44.72, 10.13) | −0.31 (−4.31, 3.69) |
| 3rd quartile | −17.39 (−45.02, 10.23) | −1.88 (−5.92, 2.15) |
| 4th quartile | −36.19 (−66.24, −6.14)* | −1.14 (−5.53, 3.25) |
Abbreviations: AFGV absolute fibroglandular volume; %FGV: percentage of fibroglandular volume; 95C%CI: 95% confidence interval
Model 1: Crude (N=329)
Model 2: Model 1 + mean kcal (total energy between puberty until 2 year after menarche onset), BMI z-score at 2 year after menarche onset, age at menarche and age at DXA and birthweight (N=329)
Model 3: Model 2 + maternal education (N=325)
*
p-value <0.05.