Table 1:

In vitro diffusion coefficient (D_m) of mucin biocoated and unbiocoated PMMA, PCRPS, PS 125–250 kDa, and PLA8 polymeric NPs in a 5% mucous gel.

Polymer Type	Dm in 5% Mucin non-biocoated (cm2/s)	Dm in 5% mucin, biocoated with 0.1% Mucins (cm2/s)	Enhancement (folds)
PMMA	1.9±0.2×10−10	1.8±0.2×10−10	0.9
PCRPS	6.8±2.9×10−08	8.8±3.4×10−08	1.3
PS 125–250	2.2±0.5×10−08	1.1±0.4×10−07	5.2
PLA8	3.4±1.5×10−08	7.3±0.1×10−07	21.3