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The chemical composition of polymer networks in hydrogels affects cell dynamics. a) Effects on cell viability: the antimicrobial side groups in the polymer network and antimicrobial precursors to prepare the polymer network can induce defects in the cell membrane and cause microbial cell death. b) Effects on cell motility: microbial cells can adhere to the hydrogel surface through non-specific or specific adhesion, which reduces cell motility.
