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. 2022 May 17;9:uhac104. doi: 10.1093/hr/uhac104

Table 4.

MLEs of parental zygote frequencies and their standard deviations and the empirical power of double reduction detection estimated from simulated data for a natural panmictic autohexaploid population under different degrees of double reduction and sample sizes

Estimates of Parental Genotype Frequencies
α = 0 1/7 1/6 1/5 1/4
Genotype True Value n = 100 200 400 100 200 400 100 200 400 100 200 400 100 200 400
6A P6 = 0.10 0.102 ± 0.065 0.103 ± 0.051 0.101 ± 0.035 0.1116 ± 0.067 0.116 ± 0.53 0.117 ± 0.040 0.118 ± 0.070 0.116 ± 0.052 0.118 ± 0.038 0.120 ± 0.070 0.121 ± 0.053 0.122 ± 0.041 0.126 ± 0.071 0.126 ± 0.053 0.127 ± 0.044
5A1a P5 = 0.05 0.046 ± 0.029 0.049 ± 0.023 0.049 ± 0.015 0.049 ± 0.030 0.052 ± 0.022 0.052 ± 0.016 0.052 ± 0.032 0.052 ± 0.022 0.052 ± 0.016 0.052 ± 0.032 0.051 ± 0.022 0.052 ± 0.016 0.052 ± 0.029 0.053 ± 0.023 0.053 ± 0.016
4A2a P4 = 0.20 0.210 ± 0.124 0.204 ± 0.092 0.199 ± 0.061 0.200 ± 0.114 0.197 ± 0.085 0.192 ± 0.059 0.200 ± 0.114 0.197 ± 0.084 0.192 ± 0.057 0.200 ± 0.115 0.191 ± 0.082 0.190 ± 0.057 0.196 ± 0.106 0.190 ± 0.077 0.186 ± 0.056
3A3a P3 = 0.25 0.228 ± 0.066 0.233 ± 0.039 0.244 ± 0.024 0.212 ± 0.067 0.218 ± 0.046 0.226 ± 0.032 0.205 ± 0.071 0.218 ± 0.045 0.224 ± 0.033 0.202 ± 0.072 0.216 ± 0.047 0.220 ± 0.037 0.201 ± 0.071 0.209 ± 0.051 0.214 ± 0.041
2A4a P2 = 0.13 0.151 ± 0.115 0.139 ± 0.072 0.137 ± 0.048 0.141 ± 0.099 0.127 ± 0.063 0.127 ± 0.043 0.136 ± 0.095 0.127 ± 0.060 0.126 ± 0.042 0.133 ± 0.088 0.129 ± 0.059 0.123 ± 0.042 0.125 ± 0.078 0.123 ± 0.057 0.121 ± 0.040
1A5a P1 = 0.10 0.103 ± 0.064 0.106 ± 0.053 0.105 ± 0.037 0.108 ± 0.069 0.105 ± 0.053 0.103 ± 0.036 0.108 ± 0.071 0.104 ± 0.051 0.103 ± 0.036 0.109 ± 0.071 0.107 ± 0.051 0.103 ± 0.036 0.106 ± 0.065 0.105 ± 0.050 0.103 ± 0.035
6a P0 = 0.17 0.161 ± 0.082 0.167 ± 0.062 0.165 ± 0.045 0.175 ± 0.079 0.183 ± 0.061 0.183 ± 0.044 0.181 ± 0.089 0.185 ± 0.060 0.185 ± 0.045 0.184 ± 0.080 0.185 ± 0.060 0.189 ± 0.045 0.194 ± 0.079 0.193 ± 0.061 0.196 ± 0.048
Rejecting null hypothesis 0.092 0.086 0.083 0.667 0.713 0.750 0.708 0.717 0.762 0.709 0.727 0.779 0.742 0.785 0.855

The proportion of rejecting the null hypothesis is the power of double reduction detection for the simulated data under α ≠ 0 and the rate of false positive discovery under α = 0.